I am always thrilled to find a bit of Shakespeare in the comic pages.
Stephen Pastis occasionally has a Shakespeare gag. His magnum opus on Mark Antony's big speech in Julius Caesar (for which, q.v.) is one of my favorites.
I've chanced upon two more, so I'm passing them along to you. They're both of the "Huge and Suspicious Setup for Horrible but Brilliant Pun on a Sunday Morning" variety. The first (click to enlarge) deals with Shakespeare more directly:
The Shakespeare in the second comes in at the end—not as the pun itself, but as a Shakespeare-related afterthought. Enjoy!