This is the reason I was particularly interested in calling your attention to Folger Copy 72 in my last post: it is the First Folio I was able to examine at the Folger Shakespeare Library when I was there in 2011.
I was drawn to this copy because of a name that is written on the verso of the frontispiece: Rachell Paule. The possibility of an early female reader of Shakespeare making markings in a copy of the First Folio—possibly revealing something of what one woman thought about Shakespeare—was too intriguing not to investigate. Alas, there were very few marks of any sort whatsoever in the volume.
But, of course, it was thrilling merely to be able to hold a First Folio, to glance through it, to search for the traces history had left on it, to contemplate its provenance—and to read portions of it!
To give you, dear readers, a sense of what that was like, I've put together this video of part of my encounter with Folger Shakespeare Library First Folio Number 72:
Music Credit: Strauss, Richard. “Also Sprach Zarathrusa.” Perf. Berlin Philharmonic Orchestra. Cond. Karl Bhohm. 2001: A Space Odyssey: Music from the Motion Picture Soundtrack. MCA Records, 1986.